Geospatial mapping, trends, and factors associated with tuberculosis treatment interruption

an ecological study

Authors

Keywords:

Tuberculosis, Epidemiology, Treatment Interruption, Spatial Analysis, Social Determinants of Health

Abstract

Objective: To analyze the spatial and temporal patterns and factors associated with tuberculosis treatment interruption in Brazil from 2010 to 2020.

Method: Ecological study using geoprocessing. The Joinpoint method was used for temporal analysis. Spatial autocorrelation and scan statistics identified clusters. Spatial and non-spatial regression models, considering p < .05, detected factors associated with the outcome.

Results: A stationary trend in tuberculosis treatment interruption was observed across the country, with increases in the Central-West and North regions. Associated socioeconomic indicators included the Gini index, household density > 2, retreatment rate, social vulnerability index, illiteracy rate, percentage of individuals in extreme poverty, and Family Health Strategy coverage.

Conclusion: Treatment interruption showed a stationary trend. Spatial regression showed that socioeconomic vulnerability indicators influence the outcome, positively or negatively, depending on the region, which calls for intensified prevention and control efforts in those areas.

Author Biographies

Maria Izabel Félix, Federal University of Piauí, Teresina, Piauí, Brazil.

Nurse. Multiprofessional Residency in Obstetric Nursing, Federal University of Piauí, Teresina, Piauí, Brazil.

Thatiana Araújo Maranhão, State University of Piauí, Parnaíba, Piauí, Brazil.

Nurse. PhD in Clinical Health Care. Professor at the State University of Piauí, Parnaíba, Piauí, Brazil.

Maria Madalena Cardoso da Frota, Federal University of Maranhão, São Luís, Maranhão, Brazil.

Nurse. PhD candidate in Public Health. Federal University of Maranhão, São Luís, Maranhão, Brazil.

Jaiana Nascimento Albuquerque, State University of Piauí, Parnaíba, Piauí, Brazil.

Undergraduate student in Nursing. State University of Piauí, Parnaíba, Piauí, Brazil.

Joana Nágila Ribeiro Figueira, State University of Piauí, Teresina, Piauí, Brazil.

Nurse. Resident in the Multiprofessional Family Health Program, State University of Piauí, Teresina, Piauí, Brazil.

Aline Miranda de Abreu, Federal University of Ceará, Fortaleza, Ceará, Brazil.

Nurse. Resident in the Multiprofessional Program in Obstetric Nursing, Federal University of Ceará, Fortaleza, Ceará, Brazil.

George Jó Bezerra Sousa, Ministry of Health, Brasília, Federal District, Brazil.

Nurse. PhD in Clinical Health Care. Works at the General Coordination of Leprosy Surveillance and Diseases in Elimination, Ministry of Health, Brasília, Federal District, Brazil.

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Published

2026-05-27

How to Cite

Maria Izabel Félix, Maranhão, T. A., da Frota, M. M. C., Albuquerque, J. N., Figueira, J. N. R., de Abreu, A. M., & Sousa, G. J. B. (2026). Geospatial mapping, trends, and factors associated with tuberculosis treatment interruption: an ecological study. Cogitare Enfermagem, 31. Retrieved from https://revistas.ufpr.br/cogitare/article/view/100798

Issue

Vol. 31 (2026)

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Original Articles

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Copyright (c) 2026 Maria Izabel Félix Rocha, Thatiana Araújo Maranhão, Maria Madalena Cardoso da Frota, Jaiana Nascimento Albuquerque, Joana Nágila Ribeiro Figueira, Aline Miranda de Abreu, George Jó Bezerra Sousa

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