Use of porcine intestinal submucous conserved in neomycin sulphate in esophagus graft in dog

Abstract

It has been verified the effectiveness of the porcine intestinal submucous as an alternative to replace three centimeters of cervical esophagus in dog and the use of neomycin sulphate as a way for the conservation of this biological membrane. In these studies sixteen adult animals were used, four animals being evaluated for seven days, four for fifteen days, four for thirty days and the remaining four were observed for forty-five days after the surgery. The postoperative evaluation consists of clinical and laboratory examinations, and at the end of the post-operation followup period they were euthanized and underwent necropsy, the grafted area was harvested for a histopathological exam. This research made it possible to conclude that the use of a biological membrane, replacing part of the canine cervical esophagus is an executable method as it allows a quick epithelial proliferation. The area of graft at the 30 days after the surgery period showed, to be not functionally effective in the studied proportions (substitution of three centimeters of cervical esophagus) displaying in all the operated animals, stenosis and consequently chokes, hypoxia, lack of nutrition and cachexia. The authors consider that the esophagus follows being a surgical challenge.