Impact of COVID-19 on cognitive function of survivors after intensive care hospitalization

prospective cohort

Authors

DOI:

https://doi.org/10.1590/ce.v30i0.96346pt

Keywords:

COVID-19, Intensive Care Units, Cognition, Cognitive Dysfunction, Mental Status and Dementia Tests

Abstract

Objective: To analyze the impact of COVID-19 on cognition in adults at 14, 30, and 90 days after discharge from the Intensive Care Unit.

Method: Prospective cohort study with 167 patients aged 18 years or older, assessed using Pfeiffer’s Short Portable Mental Status Questionnaire, with data from hospitals in the Eastern region of the state of Paraná, Brazil, between 2021 and 2022. For data analysis, Friedman’s Test was used to compare paired samples across the three collection points, and the Mann-Whitney Test was used to compare cognitive performance between men and women.

Results: The mean age was 49.3 years, with the most frequent age group being 40–49 years; 52.7% were male, and the mean length of hospitalization was 16.6 days. Cognitive alterations persisted, and female participants showed a worse recovery profile.

Conclusion: Recovery was satisfactory. Three months after ICU discharge, 4.1% of participants still presented mild impairments considering the limitations reported at the beginning of the study.

Author Biographies

Luana Caroline Kmita, Pontifical Catholic University of Paraná, Curitiba, PR, Brazil.

Physiotherapist. PhD in Health Technology. Pontifical Catholic University of Paraná, Curitiba, PR, Brazil.

Luiza Vargas Corleto, Pontifical Catholic University of Paraná, Curitiba, PR, Brazil.

Physician. Pontifical Catholic University of Paraná, Curitiba, PR, Brazil.

Maria Nesryn Tiba, Pontifical Catholic University of Paraná, Curitiba, PR, Brazil.

Physician. Master's student in Health Technology. Pontifical Catholic University of Paraná, Curitiba, PR, Brazil.

Karla Cristiane Rogal Ruggieri, Pontifical Catholic University of Paraná, Curitiba, PR, Brazil.

Physiotherapist. Master in Health Technology. Pontifical Catholic University of Paraná, Curitiba, PR, Brazil.

Rafaella Stradiotto Bernardelli, Pontifical Catholic University of Paraná, Curitiba, PR, Brazil.

Physiotherapist. PhD in Health Technology. Pontifical Catholic University of Paraná, Curitiba, PR, Brazil.

Auristela Duarte de Lima Moser, Pontifical Catholic University of Paraná, Curitiba, PR, Brazil.

Physiotherapist. PhD in Production Engineering. Pontifical Catholic University of Paraná, Curitiba, PR, Brazil.

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Published

2025-10-15

How to Cite

Kmita, L. C., Corleto, L. V., Tiba, M. N., Ruggieri, K. C. R., Bernardelli, R. S., & Moser, A. D. de L. (2025). Impact of COVID-19 on cognitive function of survivors after intensive care hospitalization: prospective cohort. Cogitare Enfermagem, 30. https://doi.org/10.1590/ce.v30i0.96346pt

Issue

Section

ORIGINAL ARTICLE