HIGH-LEVEL DISINFECTANTS ALTERNATIVE TO GLUTARALDEHYDE FOR PROCESSING FLEXIBLE ENDOSCOPES

Authors

  • Eliane Molina Psaltikidis Hospital de Clínicas da Unicamp
  • Mirtes Loeschner Leichsenring
  • Marlene Hitomi Yoshida Nakamura
  • Joaquim Murray Bustorff-Silva
  • Luis Augusto Passeri
  • Sonia Isoyama Venâncio

DOI:

https://doi.org/10.5380/ce.v19i3.35455

Keywords:

Disinfection, Endoscopes, Glutaraldehyde, Toxicity.

Abstract

Flexible endoscopes are fundamental in various
medical specialities; in general they are heat-sensitive, semicritical, and subject to high level disinfection. Glutaraldehyde
is largely used for this purpose, due to its high compatibility
and low-cost. However, its tolerance of mycobacteria and
occupational toxicity lead to pressure being applied for the
adoption of alternative germicides. A systematic review was
undertaken aiming to seek evidence regarding the effectiveness,
toxicity and potential harm caused to the endoscopes by those
germicides which are alternative to glutaraldehyde and which
are available on the market in Brazil. A total of 822 publications
was identified in 13 electronic databases, between 2008 and
2013. Of these, 23 studies were selected, considering the best
quality of evidence available. The publications point to the
superiority of peracetic acid and of orthophthaldehyde regarding
efficacy in high level disinfection. Only orthophthaldehyde
presented an adverse event clearly related to its use.
There is insufficient evidence to assert that any of these
germicides has greater potential for harm to the equipment.

Author Biography

Eliane Molina Psaltikidis, Hospital de Clínicas da Unicamp

Enfermeira assessora no Núcleo de Avaliação de Tecnologia em Saúde do HC Unicamp

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Published

2014-09-28

How to Cite

Psaltikidis, E. M., Leichsenring, M. L., Nakamura, M. H. Y., Bustorff-Silva, J. M., Passeri, L. A., & Venâncio, S. I. (2014). HIGH-LEVEL DISINFECTANTS ALTERNATIVE TO GLUTARALDEHYDE FOR PROCESSING FLEXIBLE ENDOSCOPES. Cogitare Enfermagem, 19(3). https://doi.org/10.5380/ce.v19i3.35455

Issue

Vol. 19 No. 3 (2014)

Section

Research

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