CAPACITY OF TWO SOURCES OF SELENIUM TO REDUCE HEPATOTOCIXITY CAUSED BY AFLATOXINS INGESTION

Authors

  • Antônio Sampaio Baptista
  • Adibe Luiz Abdalla
  • Deise da Silva Pires
  • Andréia Cabrini Zampronio
  • Caroline Rossim Louvandini
  • Virgílio Franco do Nascimento Filho
  • Maria Antonia Calori-Domingues
  • Eduardo Micoti da Glória
  • Mário Roberto Vizioli
  • Jorge Horii

DOI:

https://doi.org/10.5380/cep.v25i1.8398

Keywords:

MICOTOXINAS, ANTIOXIDANTE, LEVEDURA, FÍGADO, GLUTATIONA PEROXIDASE, MICOTOXINS, ANTIOXIDANT, YEAST, LIVER, GLUTATHIONE PEROXIDASE

Abstract

Eighteen wistar rats were used to evaluate the effect of sodium selenate (Na2SeO4) and of selenium originating from yeasts (SeL) on the damages induced by aflatoxins. The animals were distributed in six groups, of three repetition each: group 1 = control; group 2 = 480 mg aflatoxins kg-1 (AF); group 3 = 0.5 mg of Na2SeO4 per kg of diet; group 4 = 0.5 mg of SeL per kg of diet; group 5 = AF + 0.5 mg of Na2SeO4 per kg of diet and group 6 = AF + 0.5 mg of SeL per kg of diet. After 28 days of essay, the animals were slaughtered for the histo-pathological study. The animals of the group AF showed few hepatotoxicity signs. In the groups AF plus Na2SeO4 and AF plus SeL, the animals presented livers very well preserved. The animals that received Na2SeO4 or SeL showed some alterations. In conclusion, the sodium selenate and SeL showed potential to reduce the damages caused by aflatoxins.

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Published

2007-07-30

How to Cite

Baptista, A. S., Abdalla, A. L., Pires, D. da S., Zampronio, A. C., Louvandini, C. R., Nascimento Filho, V. F. do, … Horii, J. (2007). CAPACITY OF TWO SOURCES OF SELENIUM TO REDUCE HEPATOTOCIXITY CAUSED BY AFLATOXINS INGESTION. Boletim Do Centro De Pesquisa De Processamento De Alimentos, 25(1). https://doi.org/10.5380/cep.v25i1.8398

Issue

Vol. 25 No. 1 (2007)

Section

Artigos

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