Efficacy of Autologous Serum in Surgical Wound Healing of Dogs (Canis lupus familiaris)
DOI:
https://doi.org/10.5380/avs.v31i2.101779Keywords:
Autologous serum, modified Bates-Jensen Wound Assessment Tool, wound healing.Abstract
This study evaluated the efficacy of autologous serum (AS) in promoting the healing of primarily closed abdominal surgical wounds in female dogs using a modified Bates-Jensen Wound Assessment Too (BWAT). Thirty dogs were equally divided into Control, Treatment 1 (once-daily AS), and Treatment 2 (Twice-daily AS) groups. Wounds were assessed every other day over a 10-day postoperative period, focusing on parameters such as epithelialization, exudate, skin color, edema, necrosis, and wound edges. Findings revealed a strong positive correlation between AS application frequency and rate of epithelialization, with treatment 2 showing significant difference compared to other groups. Repeated measures ANOVA confirmed a highly significant difference among groups (p < 0.001). These results indicate that autologous serum not only accelerates wound healing but also promotes a more efficient inflammatory response without increasing the risk of complications. This study highlights Autologous Serum as biologically active, cost-effective adjunct to conventional wound management in veterinary surgery, offering practical benefits for clinical application.
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