Use of porcine intestinal submucous conserved in neomycin sulphate in esophagus graft in dog

Abstract

It has been verified the effectiveness of
the porcine intestinal submucous as an alternative to
replace three centimeters of cervical esophagus in dog
and the use of neomycin sulphate as a way for the
conservation of this biological membrane. In these
studies sixteen adult animals were used, four animals
being evaluated for seven days, four for fifteen days,
four for thirty days and the remaining four were observed
for forty-five days after the surgery. The postoperative
evaluation consists of clinical and laboratory
examinations, and at the end of the post-operation followup
period they were euthanized and underwent necropsy,
the grafted area was harvested for a histopathological
exam. This research made it possible to conclude that
the use of a biological membrane, replacing part of the
canine cervical esophagus is an executable method as
it allows a quick epithelial proliferation. The area of graft
at the 30 days after the surgery period showed, to be
not functionally effective in the studied proportions
(substitution of three centimeters of cervical esophagus)
displaying in all the operated animals, stenosis and
consequently chokes, hypoxia, lack of nutrition and
cachexia. The authors consider that the esophagus
follows being a surgical challenge.