MÚLTIPLOS EPISÓDIOS DE INFARTO AGUDO DO MIOCÁRDIO APÓS USO DE ANTICOAGULANTE - RELATO DE CASO
DOI:
https://doi.org/10.5380/rmu.v3i3.48266Keywords:
heparina, infarto do miocárdio, trombocitopenia.Abstract
Objetivo: Descrever um caso de paciente com trombocitopenia induzida por heparina (TIH) tipo II, que se manifestou através de consecutivos quadros de infartos agudos do miocárdio. Relato de Caso: Trata-se de uma paciente do sexo feminino, 70 anos, admitida no HC-UFPR por quadro de infarto agudo do miocárdio (IAM), duas semanas após internamento hospitalar por pneumonia e insuficiência cardíaca descompensada, manejadas com antibioticoterapia, heparina e diuréticos. Evoluiu com quadro de plaquetopenia a esclarecer e dois episódios subsequentes de IAM. Após a retirada da heparina, evoluiu com estabilização clínica - aumento do número de plaquetas, sem novos eventos trombótico e regularização dos testes laboratoriais. Recebeu alta hospitalar e, no retorno ambulatorial, apresentou anticorpos anti-plaqueta positivos e uma revisão de prontuário com história de múltiplas exposições a heparinas não fracionada e de baixo peso molecular. Conclusão: Diante do grande número de pacientes expostos à heparina, seus principais efeitos colaterais, dentre os quais a TIH, precisam ser conhecidos. Deve-se atentar para a possibilidade de a heparina possuir associação causal com IAM, quando associado à trombocitopenia, visto que a tendência nessas situações é de se manter a medicação a fim de evitar quadros trombóticos futuros.
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