PROCALCITONIN AS ANTIMICROBIAL MANAGEMENT TOOL IN COVID-19 PATIENTS

Authors

  • Maria Helena Lenardt
  • Clovis Cechinel
  • João Alberto Martins Rodrigues
  • Maria Angélica Binotto
  • Isabel de Lima Zanata
  • Rosane Kraus
  • Daiane Maria da Silva Marques

DOI:

https://doi.org/10.1590/ce.v28i0.89833

Keywords:

Antimicrobial Management, COVID-19, Procalcitonin, In-hospital Infection Control Services, Intensive Care Unit.

Abstract

Objective: to investigate the relationship between procalcitonin in the differential diagnosis of bacterial coinfection in COVID-19 patients.

Method: a cross-sectional retrospective study conducted between February and March 2021 in the Intensive Care Unit of a public hospital from southern Brazil by filling in a form. Descriptive statistical analyses were performed, as well as of association between variables.

Results: of the 231 patients, 28.14% presented infection (63.20% in the lungs), 25% had bacteria isolated, 77.49% used antimicrobials and, in 14.72% of the cases, procalcitonin > 2 ng/mL. There was a significant association between antimicrobial use and infection (p=0.001), isolation of bacteria (p<0.001), topography of the infection (p<0.001) and procalcitonin values (p<0.001). Procalcitonin use showed an association with bacterial infection (p<0.001), isolation of bacteria (p<0.001), antimicrobial use (p=0.001) and death (p<0.001).

Conclusion: procalcitonin can reduce empirical antimicrobial use and stimulate detection and identification of pathogens, taking into account the clinical and epidemiological data.

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Published

2023-03-31

How to Cite

Lenardt, M. H., Cechinel, C., Rodrigues, J. A. M., Binotto, M. A., Zanata, I. de L., Kraus, R., & Marques, D. M. da S. (2023). PROCALCITONIN AS ANTIMICROBIAL MANAGEMENT TOOL IN COVID-19 PATIENTS. Cogitare Enfermagem, 28. https://doi.org/10.1590/ce.v28i0.89833

Issue

Vol. 28 (2023)

Section

Research

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